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Article

Presence of interferon-λ 4, male gender, absent/mild steatosis and low viral load augment antibody levels to hepatitis C virus.

Scandinavian journal of gastroenterology - 1 Jul 2021

Waldenström Jesper, Hellstrand Kristoffer, Westin Johan, Nilsson Staffan, Christensen Peer, Färkkilä Martti, Mørch Kristine, Langeland Nina, Norkrans Gunnar, Lagging Martin

Abstract excerpt

OBJECTIVES: Despite recombinant interferon-λ 4 (IFN-λ4) demonstrating anti-viral activity in vitro and the ancestral functional gene (IFNL4) being conserved in all other primates, there has been speculation that IFN-λ4 may be detrimental in humans. In light of recent rekindled interest in humoral immunity, this study aimed at evaluating the impact of baseline characteristics, including IFNL4, on antibody levels...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34078234
DOI: 10.1080/00365521.2021.1922750

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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