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Article

A genetic variant in toll-like receptor 5 is linked to chemokine levels and hepatocellular carcinoma in steatohepatitis.

Liver international : official journal of the International Association for the Study of the Liver - 1 Sept 2021

Nischalke Hans Dieter, Fischer Janett, Klüners Alexandra, Matz-Soja Madlen, Krämer Benjamin, Langhans Bettina, Goeser Felix, Soyka Michael, Stickel Felix, Spengler Ulrich, Nattermann Jacob, Strassburg Christian P, Berg Thomas, Lutz Philipp

Abstract excerpt

BACKGROUND & AIMS: Bacterial translocation drives liver disease progression. We investigated whether functional genetic variants in toll-like receptor 5 (TLR5), the receptor for bacterial flagellin, affect the risk for hepatocellular carcinoma (HCC). METHODS: Healthy controls (n = 212), patients with alcohol abuse without liver disease (n = 382), and patients from a discovery cohort of alcohol-associated...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 34051061
DOI: 10.1111/liv.14980

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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