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Article

Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infection.

Journal of hepatology - 1 Oct 2009

Li Yonghong, Chang Monica, Abar Olivia, Garcia Veronica, Rowland Charles, Catanese Joseph, Ross David, Broder Samuel, Shiffman Mitchell, Cheung Ramsey, Wright Teresa, Friedman Scott L, Sninsky John

Abstract excerpt

BACKGROUND/AIMS: Seven genomic loci, implicated by single nucleotide polymorphisms (SNPs), have recently been associated with progression to advanced fibrosis (fibrosis risk) in patients with chronic hepatitis C virus. Other variants in these loci have not been examined but may be associated with fibrosis risk independently of or due to linkage disequilibrium with the original polymorphisms. METHODS: We carried...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19586676
DOI: 10.1016/j.jhep.2009.04.027
PMCID: PMC2883297

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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