Article
Association between TLR2, TLR4, and TLR5 genetic variants and the risk of hepatocellular carcinoma in Moroccan population.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2023
Zerrad Chaimaa, Lkhider Mustapha, Belkouchi Abdelkader, Tanouti Ikram-Allah, Badre Wafaa, Tahiri Mohamed, Ayassi Sarra, Marchio Agnès, Pineau Pascal, Benjelloun Soumaya, Ezzikouri Sayeh
Abstract excerpt
Hepatocellular carcinoma (HCC) is the fifth most common human malignancy and the fourth most frequent cause of cancer-related deaths worldwide. Toll-like receptors (TLRs), are known to play a key role in hepatocarcinogenesis through induction of inflammation. We aimed to investigate the association between TLR2 rs3804099, TLR4 rs4986790, rs4986791, and rs11536889 and TLR5 rs5744174 and HCC risk in a total of 306...