Article
Polymorphisms in the CYP2A6 and ABCC4 genes are associated with a protective effect on chronic myeloid leukemia in the Brazilian Amazon population.
Molecular genetics & genomic medicine - 1 Jul 2021
Monte Natasha, Pantoja Karla B C C, Rodrigues Juliana C G, de Carvalho Darlen C, Azevedo Tereza C B, Pereira Esdras E B, de Assumpção Paulo P, Dos Santos Sidney E B, Fernandes Marianne R, Dos Santos Ney P C
Abstract excerpt
BACKGROUND: Susceptibility to Chronic Myeloid Leukemia (CML) may be modulated by genetic variables. However, the majority of previous investigations have focused on genetically homogeneous populations, resulting in a lack of evidence on how genetic factors may influence the development of CML in miscegenated populations. We analyzed 30 polymorphisms in genes related to DNA repair, folate metabolism, transmembrane...
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