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Article

Impact of DNA methylation on 3D genome structure.

Nature communications - 28 May 2021

Buitrago Diana, Labrador Mireia, Arcon Juan Pablo, Lema Rafael, Flores Oscar, Esteve-Codina Anna, Blanc Julie, Villegas Nuria, Bellido David, Gut Marta, Dans Pablo D, Heath Simon C, Gut Ivo G, Brun Heath Isabelle, Orozco Modesto

Abstract excerpt

Determining the effect of DNA methylation on chromatin structure and function in higher organisms is challenging due to the extreme complexity of epigenetic regulation. We studied a simpler model system, budding yeast, that lacks DNA methylation machinery making it a perfect model system to study the intrinsic role of DNA methylation in chromatin structure and function. We expressed the murine DNA...

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Identifiers

PMID: 34050148
DOI: 10.1038/s41467-021-23142-8
PMCID: PMC8163762

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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