Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Monovalent: Divalent Anion Selectivity in the CFTR Channel Pore.

Cell biochemistry and biophysics - 1 Dec 2021

Linsdell Paul

Abstract excerpt

The cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel shows only weak selectivity between different small monovalent anions, however, little is known about its ability to discriminate between monovalent and divalent anions. The present study uses patch clamp recording to investigate the interaction between the small divalent anions S2O32- and SO42- and wild-type and pore-mutant forms of human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anions
Share to Chlorides
Share to Cystic Fibrosis Transmembrane Conductance Regulator

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Membrane Potentials

Share to Mutation

Share to Patch-Clamp Techniques

Source

Identifiers

PMID: 34031860
DOI: 10.1007/s12013-021-00998-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Monovalent: Divalent Anion Selectivity in the CFTR Channel Pore.PMID 34031860Read ↗

Trivalent anions as probes of the CFTR channel pore.Semantic proximity Read ↗

Mutation-induced blocker permeability and multiion block of the CFTR chloride channel pore.Semantic proximity Read ↗

Interactions between permeant and blocking anions inside the CFTR chloride channel pore.Semantic proximity Read ↗

Anion conductance selectivity mechanism of the CFTR chloride channel.Semantic proximity Read ↗

Role of Hydrophobic Amino-Acid Side-Chains in the Narrow Selectivity Filter of the CFTR Chloride Channel Pore in Conductance and Selectivity.Semantic proximity Read ↗

Cystic fibrosis transmembrane conductance regulator. Physical basis for lyotropic anion selectivity patterns.Semantic proximity Read ↗

Direct comparison of the functional roles played by different transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore.Semantic proximity Read ↗

Structural identification of a selectivity filter in CFTRSemantic proximity Read ↗

Regulation of CFTR chloride channel macroscopic conductance by extracellular bicarbonate.Semantic proximity Read ↗

Pseudohalide anions reveal a novel extracellular site for potentiators to increase CFTR function.Semantic proximity Read ↗

Two serial filters determine P2X7R cation selectivity, Ser342 in the central pore and lateral acidic residues at the cytoplasmic interfaceSemantic proximity Read ↗

Ion conduction and selectivity in acid-sensing ion channel 1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.