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Article

Loss of H3K27 trimethylation is frequent in IDH1-R132H but not in non-canonical IDH1/2 mutated and 1p/19q codeleted oligodendroglioma: a Japanese cohort study.

Acta neuropathologica communications - 21 May 2021

Habiba Umma, Sugino Hirokazu, Yordanova Roumyana, Ise Koki, Tanei Zen-Ichi, Ishida Yusuke, Tanikawa Satoshi, Terasaka Shunsuke, Sato Ken-Ichi, Kamoshima Yuuta, Katoh Masahiko, Nagane Motoo, Shibahara Junji, Tsuda Masumi, Tanaka Shinya

Abstract excerpt

Oligodendrogliomas are defined by mutation in isocitrate dehydrogenase (NADP(+)) (IDH)1/2 genes and chromosome 1p/19q codeletion. World Health Organisation diagnosis endorses testing for 1p/19q codeletion to distinguish IDH mutant (Mut) oligodendrogliomas from astrocytomas because these gliomas require different treatments and they have different outcomes. Several methods have been used to identify 1p/19q status;...

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Identifiers

PMID: 34020723
DOI: 10.1186/s40478-021-01194-7
PMCID: PMC8138926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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