Article
Reclassification of 400 consecutive glioma cases based on the revised 2016WHO classification.
Brain tumor pathology - 1 Apr 2018
Akagi Yojiro, Yoshimoto Koji, Hata Nobuhiro, Kuga Daisuke, Hatae Ryusuke, Amemiya Takeo, Sangatsuda Yuhei, Suzuki Satoshi O, Iwaki Toru, Mizoguchi Masahiro, Iihara Koji
Abstract excerpt
In this study, we reclassified 400 consecutive glioma cases including pediatric cases, using the revised 2016 WHO classification with samples collected from the Kyushu University Brain Tumor Bank. The IDH1/2, H3F3A, key genetic markers in the 2016 classification, were analyzed using high-resolution melting, with DNA extracted from frozen tissues. The 1p/19q codeletions were evaluated using a microsatellite-based...
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