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Article

IDH mutation, 1p19q codeletion and ATRX loss in WHO grade II gliomas.

Oncotarget - 6 Oct 2015

Leeper Heather E, Caron Alissa A, Decker Paul A, Jenkins Robert B, Lachance Daniel H, Giannini Caterina

Abstract excerpt

BACKGROUND: Epigenetic, genetic, and molecular studies have identified several diagnostic and prognostic markers in diffuse gliomas. Their importance for evaluating WHO grade II gliomas has yet to be specifically delineated. METHODS: We analyzed markers, including IDH mutation(IDHmut), 1p19q codeletion(1p19qcodel), ATRX expression loss(ATRX loss) and p53 overexpression, and outcomes in 159 patients with WHO grade...

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PMID: 26210286
DOI: 10.18632/oncotarget.4497
PMCID: PMC4745799

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ATRX

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