Article
Whole-Genome Sequencing of Common Salivary Gland Carcinomas: Subtype-Restricted and Shared Genetic Alterations.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2021
Karpinets Tatiana V, Mitani Yoshitsugu, Liu Bin, Zhang Jianhua, Pytynia Kristen B, Sellen Linton D, Karagiannis Danice T, Ferrarotto Renata, Futreal Andrew P, El-Naggar Adel K
Abstract excerpt
PURPOSE: Salivary gland carcinomas (SGCs) are pathologically classified into several widely diverse subtypes, of which adenoid cystic carcinoma (ACC), mucoepidermoid carcinoma (MEC), and salivary duct carcinoma (SDC) are the most commonly encountered. A comparative genetic analysis of these subtypes provides detailed information on the genetic alterations that are associated with their tumorigenesis and may lead...
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