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Identification of Fusion Genes and Targets for Genetically Matched Therapies in a Large Cohort of Salivary Gland Cancer Patients

27 Aug 2022

Abstract excerpt

Introduction: Salivary gland cancer (SGC) is a rare cancer for which systemic treatment options are limited. Therefore, it is important to characterize its genetic landscape in search for actionable aberrations, such as NTRK gene fusions. This research aimed to identify these actionable aberrations by combining NGS-based analysis of RNA (gene fusions) and DNA (single and multiple nucleotide variants, copy number...

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Ear and Head Tumors
Salivary Gland Tumors Diagnosis and Treatment
Tumors and Oncological Cases

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36077692
DOI: 10.3390/cancers14174156

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