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Article

Detailed genome-wide SNP analysis of major salivary carcinomas localizes subtype-specific chromosome sites and oncogenes of potential clinical significance.

The American journal of pathology - 1 Jun 2013

Zhang Li, Mitani Yoshitsugu, Caulin Carlos, Rao Pulivarthi H, Kies Merrill S, Saintigny Pierre, Zhang Nianxiang, Weber Randal S, Lippman Scott M, El-Naggar Adel K

Abstract excerpt

The molecular genetic alterations underlying the development and diversity of salivary gland carcinomas are largely unknown. To characterize these events, comparative genomic hybridization analysis was performed, using a single-nucleotide polymorphism microarray platform, of 60 fresh-frozen specimens that represent the main salivary carcinoma types: mucoepidermoid carcinoma (MEC), adenoid cystic carcinoma (ACC),...

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Topics

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Share to Carcinoma, Adenoid Cystic
Share to Carcinoma, Ductal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA Copy Number Variations

Share to Neoplasm Grading

Share to Neoplasm Staging

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Source

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Identifiers

PMID: 23583282
DOI: 10.1016/j.ajpath.2013.02.020
PMCID: PMC3668022

Genes

CCL4
CCND3
CNOT2
ERBB2
NUMA1
PAX5

Provenance

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