Article
Mutational landscape of primary pulmonary salivary gland-type tumors through targeted next-generation sequencing.
Lung cancer (Amsterdam, Netherlands) - 1 Oct 2021
Wang Fang, Xi Shao-Yan, Hao Wen-Wen, Yang Xin-Hua, Deng Ling, Xu Yu-Xia, Wu Xiao-Yan, Zeng Liang, Guo Kai-Hua, Wang Hai-Yun
Abstract excerpt
OBJECTIVES: Primary pulmonary salivary gland-type tumors (PSGTs) mainly comprise of mucoepidermoid carcinoma (MEC) and adenoid cystic carcinoma (ACC), which are rare and molecularly poorly understood. This study aimed to profile the molecular alterations of PSGTs via targeted next-generation sequencing (NGS). MATERIAL AND METHODS: Immunohistochemistry was used to screen PSGTs in 32 patients and MAML2 and MYB...
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