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Article

Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma

9 Feb 2016

Abstract excerpt

Adenoid cystic carcinomas (ACC) of the salivary glands are challenging to understand, treat, and cure. To better understand the genetic alterations underlying the pathogenesis of these tumors, we performed comprehensive genome analyses of 25 fresh-frozen tumors, including whole-genome sequencing and expression and pathway analyses. In addition to the well-described MYB-NFIB fusion that was found in 11 tumors...

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Share to Oral and Maxillofacial Pathology
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PMID: 26862087
DOI: 10.1158/1940-6207.capr-15-0316

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