The landscape of gene fusions and somatic mutations in salivary gland neoplasms - Implications for diagnosis and therapy.

Abstract excerpt

Recent studies of the genomic landscape of salivary gland tumors have provided important insights into the molecular pathogenesis of these tumors. The most consistent alterations identified include a translocation-generated gene fusion network involving transcription factors, transcriptional coactivators, tyrosine kinase receptors, and other kinases. In addition, next-generation sequencing studies of a few...

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