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Article

Whole-Exome Sequencing of Salivary Gland Mucoepidermoid Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2017

Kang Hyunseok, Tan Marietta, Bishop Justin A, Jones Siân, Sausen Mark, Ha Patrick K, Agrawal Nishant

Abstract excerpt

PURPOSE: Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. To explore the genetic origins of MEC, we performed systematic genomic analyses of these tumors. EXPERIMENTAL DESIGN: Whole-exome sequencing and gene copy-number analyses were performed for 18 primary cancers with matched normal tissue. FISH was used to determine the presence or absence of the MECT1-MAML2 translocation in 17...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Neoplasm Grading

Share to Neoplasm Metastasis

Share to Oncogene Proteins, Fusion

Share to Salivary Gland Neoplasms

Share to Translocation, Genetic

Source

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Identifiers

PMID: 27340278
DOI: 10.1158/1078-0432.CCR-16-0720
PMCID: PMC5182193

Genes

MAML2
ERBB4
IRAK1
ITGAL
OBSCN
OTOGL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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