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Inflammatory Diseases, Inflammatory Biomarkers, and Alzheimer Disease: An Observational Analysis and Mendelian Randomization.

Neurology - 7 Feb 2023

Huang Jian, Su Bowen, Karhunen Ville, Gill Dipender, Zuber Verena, Ahola-Olli Ari, Palaniswamy Saranya, Auvinen Juha, Herzig Karl-Heinz, Keinänen-Kiukaanniemi Sirkka, Salmi Marko, Jalkanen Sirpa, Lehtimäki Terho, Salomaa Veikko, Raitakari Olli T, Matthews Paul M, Elliott Paul, Tsilidis Konstantinos K, Jarvelin Marjo-Riitta, Tzoulaki Ioanna, Dehghan Abbas

Abstract excerpt

BACKGROUND AND OBJECTIVES: Whether chronic autoimmune inflammatory diseases causally affect the risk of Alzheimer disease (AD) is controversial. We characterized the relationship between inflammatory diseases and risk of AD and explored the role of circulating inflammatory biomarkers in the relationships between inflammatory diseases and AD. METHODS: We performed observational analyses for chronic autoimmune...

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Identifiers

PMID: 36384659
DOI: 10.1212/WNL.0000000000201489
PMCID: PMC9946179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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