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Article

Peripheral blood immune cell phenotypes and Alzheimer's disease: A mediation Mendelian randomization study.

Journal of Alzheimer's disease : JAD - 1 May 2025

Sun Jiahui, Teng Fei, Cao Yu, Pei Hui, Ma Lina, Wei Wei, Li Hao

Abstract excerpt

BackgroundAlzheimer's disease (AD) is a debilitating neurodegenerative disorder. Although peripheral immune cells have been implicated in the pathology of AD, the causal relationship between peripheral blood immune cells and AD remains to be fully elucidated.ObjectiveTo examine the association between peripheral blood immune cell phenotypes and AD, mediated by peripheral blood metabolite, a two-step Mendelian...

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Identifiers

PMID: 40232262
DOI: 10.1177/13872877251330503

Genes

C2
C3
CD38

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