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Systemic inflammatory markers in relation to cognitive function and measures of brain atrophy: a Mendelian randomization study

11 Jun 2022

Abstract excerpt

Abstract Observational studies have implied associations between multiple cytokines and cognitive decline, anti-inflammatory drugs however did not yield any protective effects on cognitive decline. We aimed to assess the associations of systemic inflammation, as measured by multiple cytokine and growth factor, with cognitive performance and brain atrophy using two-sample Mendelian randomization (MR). Independent...

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PMID: 35689786
DOI: 10.1007/s11357-022-00602-7

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