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Causal effects of circulating cytokine concentrations on risk of Alzheimer’s disease: A bidirectional two-sample Mendelian randomization study

2020-11-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> There is considerable interest in the role of neuroinflammation in the pathogenesis of Alzheimer’s disease. Evidence from observational studies suggests an association between cytokine concentrations and Alzheimer’s disease. However, establishing a causal role of cytokine concentrations on risk of Alzheimer’s disease is challenging due to bias from reverse causation and residu...

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Literature Corpus work
8771a68c-5ece-5cf4-8409-c8ce3b186629
DOI
10.1101/2020.11.18.20232629
Open publication

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