Article
Immunity and amyloid beta, total tau and neurofilament light chain: Findings from a community-based cohort study.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Mar 2021
Fani Lana, Ahmad Shahzad, Ikram M Kamran, Ghanbari Mohsen, Ikram M Arfan
Abstract excerpt
INTRODUCTION: We investigated how components of immunity relate to biomarkers of Alzheimer's disease (AD) in plasma and explored the influence of AD genetic risk factors in the population-based Rotterdam Study. METHODS: In 7397 persons, we calculated the granulocyte-to-lymphocyte ratio (GLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII). In 3615 of these persons, plasma...
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