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Article

Impact of MMP2 rs243865 and MMP3 rs3025058 Polymorphisms on Clinical Findings in Alzheimer's Disease Patients.

Mediators of inflammation - 1 Jan 2021

Durmanova Vladimira, Javor Juraj, Parnicka Zuzana, Minarik Gabriel, Ocenasova Agata, Vaseckova Barbora, Reznakova Veronika, Kralova Maria, Hromadka Tomas, Shawkatova Ivana

Abstract excerpt

Alzheimer's disease (AD) is a chronic neurodegenerative disease of the central nervous system with higher prevalence in elderly people. Despite numerous research studies, the etiopathogenesis of AD remains unclear. Matrix metalloproteinases (MMPs) are endopeptidases involved in the cleavage of extracellular matrix proteins and basement membrane compounds. In the brain, the pathological role of MMPs includes the...

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Identifiers

PMID: 33986628
DOI: 10.1155/2021/5573642
PMCID: PMC8079184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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