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Article

Correlation between MMP-3-1171 5A/6A polymorphism and the risk of Alzheimer's disease: A meta-analysis.

Medicine - 11 Sept 2026

Wang Yan, Zhu Shaohui, Ma Yanjiao, Chen Xiaoshan, Zhou Minhua

Abstract excerpt

BACKGROUND: Previous studies of matrix metalloproteinase-3 (MMP-3) -1171 5A/6A polymorphism in Alzheimer's disease (AD) have been extensively investigated; however, the results from different studies are inconsistent. This meta-analysis was performed to clarify the link between this variant and AD. METHODS: We searched PubMed, Embase, Chinese National Knowledge Infrastructure and Wanfang Database. The...

Read the complete abstract on PubMed

Topics

Humans
Alzheimer Disease
Asian People
Case-Control Studies
Genetic Predisposition to Disease
Matrix Metalloproteinase 3

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Odds Ratio

Polymorphism, Genetic

Polymorphism, Single Nucleotide

Risk Factors

White People

Source

Open in PubMed Open full text

Identifiers

PMID: 42742624
DOI: 10.1097/MD.0000000000050560
PMCID: PMC13574472

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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