Article
Genetic association between matrix metalloproteinase MMP-9 and MMP-3 polymorphisms and Japanese sporadic Alzheimer's disease.
Neurobiology of aging - 1 Jul 2005
Shibata Nobuto, Ohnuma Tohru, Higashi Shinji, Usui Chie, Ohkubo Taku, Kitajima Akiyoshi, Ueki Akira, Nagao Masatsugu, Arai Heii
Abstract excerpt
Recent studies suggested that matrix metalloproteinases (MMPs) might play an important role in the pathophysiology of Alzheimer's disease (AD). MMP-9 and MMP-3 are reported to degrade amyloid beta and have several functional polymorphisms associated with other common diseases. Four common polymor...
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