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Article

Lymphoblastic transformation of follicular lymphoma: a clinicopathologic and molecular analysis of 7 patients.

Human pathology - 1 Feb 2015

Geyer Julia Turbiner, Subramaniyam Shivakumar, Jiang Yanwen, Elemento Olivier, Ferry Judith A, de Leval Laurence, Nakashima Megan O, Liu Yen-Chun, Martin Peter, Mathew Susan, Orazi Attilio, Tam Wayne

Abstract excerpt

Approximately 30% of patients with follicular lymphoma (FL) transform to a more aggressive malignancy, most commonly diffuse large B cell lymphoma. Rarely, FL transformation results in clinical findings, histology, and immunophenotype reminiscent of B-lymphoblastic leukemia/lymphoma. We report the largest series to date with detailed analysis of 7 such patients. Lymphoblastic transformation occurred on average 2...

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Share to Gene Rearrangement
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunophenotyping

Share to Lymphocyte Activation

Share to Lymphoma, B-Cell

Share to Lymphoma, Follicular

Share to Pathology, Molecular

Share to Proto-Oncogene Proteins c-bcl-6

Source

Identifiers

PMID: 25529125
DOI: 10.1016/j.humpath.2014.10.021

Genes

BCL2
CCND3
CDK12
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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