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Article

MYC and Aggressive B-cell Lymphomas

13 Apr 2011

Abstract excerpt

Rearrangement of the proto-oncogene MYC leads to MYC protein deregulation and is an important driver of oncogenic transformation. MYC rearrangement is a recurring genetic abnormality in several aggressive B-cell lymphomas including: Burkitt lymphoma, diffuse large B-cell lymphoma; B-cell lymphoma, unclassifiable with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma; rare de novo...

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PMID: 21490439
DOI: 10.1097/pap.0b013e3182169948

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