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Article

Incidence and Clinical Significance of Bcl-2 / IgH Rearrangements in Follicular Lymphoma

20 Nov 2002

Abstract excerpt

Bcl-2/IgH rearrangement is the molecular hallmark of follicular lymphoma (FL) which is present in 70-90% of the cases at diagnosis. The clinical significance of this feature is controversial. The aim of this study was to analyze the bcl-2/IgH rearrangement by means of a PCR technique, and to correlate molecular findings with clinical characteristics and outcome. Sixty-nine patients (median age, 53 years;...

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PMID: 12691144
DOI: 10.1080/1042819021000050052

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