Article
Utility of immunohistochemistry with an antibody against MYC at the initial diagnosis of follicular lymphoma, grade 3A, for predicting a more aggressive clinical course: a case report and review of the literature.
International journal of clinical and experimental pathology - 1 Jan 2015
Ichikawa Kunimoto, Aritaka Nanae, Ogura Kanako, Hosone Masaru, Ota Yasunori, Sato Eriko, Komatsu Norio, Hirano Takao
Abstract excerpt
Follicular lymphoma (FL) is the most common indolent lymphoma, and associated with the chromosomal translocation t(14;18)(q32;q21). While, FL harboring both BCL2 and MYC translocation at diagnosis is very rare. The evaluation of MYC expression in typical FL at presentation using southern blot, G-banded karyotyping or fluorescence in situ hybridization (FISH) analyses has been described so far. However, there are...
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