Clinicopathological and genomic analysis of double-hit follicular lymphoma: comparison with high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements.

doi:10.1038/modpathol.2017.134

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Article

Clinicopathological and genomic analysis of double-hit follicular lymphoma: comparison with high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2018

Miyaoka Masashi, Kikuti Yara Y, Carreras Joaquim, Ikoma Haruka, Hiraiwa Shinichiro, Ichiki Akifumi, Kojima Minoru, Ando Kiyoshi, Yokose Tomoyuki, Sakai Rika, Hoshikawa Masahiro, Tomita Naoto, Miura Ikuo, Takata Katsuyoshi, Yoshino Tadashi, Takizawa Jun, Bea Silvia, Campo Elias, Nakamura Naoya

Abstract excerpt

Most high-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements are aggressive B-cell lymphomas. Occasional double-hit follicular lymphomas have been described but the clinicopathological features of these tumors are not well known. To clarify the characteristics of double-hit follicular lymphomas, we analyzed 10 cases of double-hit follicular lymphomas and 15 cases of high-grade B-cell lymphomas...

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Identifiers

PMID: 28984304
DOI: 10.1038/modpathol.2017.134

Genes

MYC
BCL2
BCL6
IGH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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