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Article

BCL6-translocations affect the phenotype of follicular lymphomas only in the absence of t(14;18)IgH/BCL2.

Anticancer research - 1 Nov 2009

Gollub Wiebke, Stassek Björn, Huckhagel Torge, Bernd Heinz-Wolfram, Krokowski Manuela, Merz Hartmut, Feller Alfred Christian, Thorns Christoph

Abstract excerpt

BACKGROUND: The translocation t(14;18)IgH/BCL2 is the molecular hallmark of follicular lymphomas (FL). A subset of cases harbours translocations involving the BCL6-gene locus. This study aimed to determine the frequency of BCL2- and BCL6-translocations in FL and to identify morphological and immuno-histochemical features with respect to the presence of BCL2- and BCL6-translocations. MATERIALS AND METHODS:...

Read the complete abstract on PubMed

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Share to Chromosomes, Human, Pair 14
Share to Chromosomes, Human, Pair 18

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunoglobulin Heavy Chains

Share to In Situ Hybridization, Fluorescence

Share to Lymphoma, Follicular

Share to Proto-Oncogene Proteins c-bcl-2

Share to Proto-Oncogene Proteins c-bcl-6

Share to Translocation, Genetic

Source

Identifiers

PMID: 20032416

Genes

BCL6
BCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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BCL6-translocations affect the phenotype of follicular lymphomas only in the absence of t(14;18)IgH/BCL2.PMID 20032416Read ↗

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