Article
The clinical and molecular taxonomy of t(14;18)-negative follicular lymphomas.
Blood advances - 26 Sept 2023
Salaverria Itziar, Weigert Oliver, Quintanilla-Martinez Leticia
Abstract excerpt
Follicular lymphoma (FL) is a neoplasm derived from germinal center B cells, composed of centrocytes and centroblasts, with at least a focal follicular growth pattern. The t(14;18) translocation together with epigenetic deregulation through recurrent genetic alterations are now recognized as the hallmark of FL. Nevertheless, FL is a heterogeneous disease, clinically, morphologically, and biologically. The...
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