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Article

The potential role of nucleophosmin (NPM1) in the development of cancer.

Journal of cellular physiology - 1 Nov 2021

Karimi Dermani Fateme, Gholamzadeh Khoei Saeideh, Afshar Saeid, Amini Razieh

Abstract excerpt

Nucleophosmin (NPM1) is a well-known nucleocytoplasmic shuttling protein that performs several cellular functions such as ribosome biogenesis, chromatin remodeling, genomic stability, cell cycle progression, and apoptosis. NPM1 has been identified to be necessary for normal cellular functions, and its altered regulation by overexpression, mutation, translocation, loss of function, or sporadic deletion can lead to...

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Identifiers

PMID: 33959979
DOI: 10.1002/jcp.30406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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