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Article

Role of MicroRNA-145 in DNA Damage Signalling and Senescence in Vascular Smooth Muscle Cells of Type 2 Diabetic Patients.

Cells - 16 Apr 2021

Hemmings Karen E, Riches-Suman Kirsten, Bailey Marc A, O'Regan David J, Turner Neil A, Porter Karen E

Abstract excerpt

Increased cardiovascular morbidity and mortality in individuals with type 2 diabetes (T2DM) is a significant clinical problem. Despite advancements in achieving good glycaemic control, this patient population remains susceptible to macrovascular complications. We previously discovered that vascular smooth muscle cells (SMC) cultured from T2DM patients exhibit persistent phenotypic aberrancies distinct from those...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33923614
DOI: 10.3390/cells10040919
PMCID: PMC8073820

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