Article
Vascular Smooth Muscle as a Target for Novel Therapeutics.
Current diabetes reports - 1 Oct 2015
Porter Karen E, Riches Kirsten
Abstract excerpt
Cardiovascular disease is the principal cause of death in patients with type 2 diabetes (T2DM). Exposure of the vasculature to metabolic disturbances leaves a persistent imprint on vascular walls, and specifically on smooth muscle cells (SMC) that favours their dysfunction and potentially underlies macrovascular complications of T2DM. Current diabetes therapies and continued development of newer treatments has...
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