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Article

Transcriptional regulation of <i>Foxp3</i> gene: Multiple signal pathways on the road

6 Mar 2009

Abstract excerpt

Foxp3, forkhead/winged helix transcription factor 3, is a master transcription factor for the development and function of regulatory T cells. Foxp3 has been proved to be associated with immunoregulation, autoimmune diseases, infections, and tumor immune evasion/escape. Foxp3 regulates other critical gene transcriptions. However, the mechanism how the transcription of Foxp3 itself is regulated remains partly...

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PMID: 19267400
DOI: 10.1002/med.20152

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