Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Shared genetic etiology and causality between body fat percentage and cardiovascular diseases: a large-scale genome-wide cross-trait analysis.

BMC medicine - 29 Apr 2021

Zhuang Zhenhuang, Yao Minhao, Wong Jason Y Y, Liu Zhonghua, Huang Tao

Abstract excerpt

BACKGROUND: Accumulating evidences have suggested that high body fat percentage (BF%) often occurs in parallel with cardiovascular diseases (CVDs), implying a common etiology between them. However, the shared genetic etiology underlying BF% and CVDs remains unclear. METHODS: Using large-scale genome-wide association study (GWAS) data, we investigated shared genetics between BF% (N = 100,716) and 10 CVD-related...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Cardiovascular Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Associations and Epidemiology

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 33910581
DOI: 10.1186/s12916-021-01972-z
PMCID: PMC8082910

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Shared genetic etiology and causality between body fat percentage and cardiovascular diseases: a large-scale genome-wide cross-trait analysis.PMID 33910581Read ↗

Genetic evidence prioritizes circulating proteins for heart failure beyond shared BMI-related genetic liabilitySemantic proximity Read ↗

Decoding the genetic crosstalk network for cardiometabolic diseases and metabolic traitsSemantic proximity Read ↗

Multi-trait analysis reveals risk loci for heart failure and the shared genetic etiology with blood lipids, blood pressure, and blood glucose.Semantic proximity Read ↗

Genetic crossroads of cardiovascular disease and its comorbidities: Toward holistic therapeutic strategiesSemantic proximity Read ↗

A mechanistic framework for cardiometabolic and coronary artery diseases.Semantic proximity Read ↗

Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States.Semantic proximity Read ↗

A framework to decipher the genetic architecture of combinations of complex diseases: applications in cardiovascular medicine.Semantic proximity Read ↗

Genetic Factor Analysis for Characterizing Phenome-Wide Patterns of Genetic PleiotropySemantic proximity Read ↗

Genetic crossroads of cardiovascular disease and its comorbidities: toward holistic therapeutic strategies.Semantic proximity Read ↗

Mapping the genetic landscape of eight common cardiovascular diseasesSemantic proximity Read ↗

Genome-wide insights into the shared genetic landscape between metabolic dysfunction-associated fatty liver disease and cardiovascular diseasesSemantic proximity Read ↗

Integrated Genomic and Transcriptomic Analysis Reveals the Genetic Basis and Causal Association Between Obesity and Atrial Fibrillation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.