Article
Two opposite voltage-dependent currents control the unusual early development pattern of embryonic Renshaw cell electrical activity.
eLife - 26 Apr 2021
Boeri Juliette, Meunier Claude, Le Corronc Hervé, Branchereau Pascal, Timofeeva Yulia, Lejeune François-Xavier, Mouffle Christine, Arulkandarajah Hervé, Mangin Jean Marie, Legendre Pascal, Czarnecki Antonny
Abstract excerpt
Renshaw cells (V1R) are excitable as soon as they reach their final location next to the spinal motoneurons and are functionally heterogeneous. Using multiple experimental approaches, in combination with biophysical modeling and dynamical systems theory, we analyzed, for the first time, the mechanisms underlying the electrophysiological properties of V1R during early embryonic development of the mouse spinal cord...
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