Article

Rebuilding Spinal Circuit Computation Through a Patient-Specific Interneuron Precision Model

2025-12-15

Abstract excerpt

Spinal interneurons constitute the computational core of spinal circuitry, integrating excitatory and inhibitory inputs to generate the rhythmic patterns that drive locomotor, postural, and autonomic control. Their developmental logic, molecular diversity, and adaptive plasticity make them central determinants of functional recovery after spinal cord injury. Yet most regenerative strategies continue to emphasize c...

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Literature Corpus work: e83aa04d-554a-5b2a-9c21-03f055702459
DOI: 10.20944/preprints202512.1323.v1

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