Article
Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch.
Science (New York, N.Y.) - 11 Sept 2015
Dehorter Nathalie, Ciceri Gabriele, Bartolini Giorgia, Lim Lynette, del Pino Isabel, Marín Oscar
Abstract excerpt
The function of neural circuits depends on the generation of specific classes of neurons. Neural identity is typically established near the time when neurons exit the cell cycle to become postmitotic cells, and it is generally accepted that, once the identity of a neuron has been established, its fate is maintained throughout life. Here, we show that network activity dynamically modulates the properties of...
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