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Article

Role of the SOS Response in the Generation of Antibiotic Resistance In Vivo.

Antimicrobial agents and chemotherapy - 17 Jun 2021

Crane John K, Alvarado Cassandra L, Sutton Mark D

Abstract excerpt

The SOS response to DNA damage is a conserved stress response in Gram-negative and Gram-positive bacteria. Although this pathway has been studied for years, its relevance is still not familiar to many working in the fields of clinical antibiotic resistance and stewardship. Under some conditions, the SOS response favors DNA repair and preserves the genetic integrity of the organism. On the other hand, the SOS...

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Identifiers

PMID: 33875437
DOI: 10.1128/AAC.00013-21
PMCID: PMC8373240

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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