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Article

Effects of Stress, Reactive Oxygen Species, and the SOS Response on De Novo Acquisition of Antibiotic Resistance in Escherichia coli.

Antimicrobial agents and chemotherapy - 14 Dec 2015

Händel Nadine, Hoeksema Marloes, Freijo Mata Marina, Brul Stanley, ter Kuile Benno H

Abstract excerpt

Strategies to prevent the development of antibiotic resistance in bacteria are needed to reduce the threat of infectious diseases to human health. The de novo acquisition of resistance due to mutations and/or phenotypic adaptation occurs rapidly as a result of interactions of gene expression and mutations (N. Handel, J. M. Schuurmans, Y. Feng, S. Brul, and B. H. Ter Kuile, Antimicrob Agents Chemother...

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Identifiers

PMID: 26666928
DOI: 10.1128/AAC.02684-15
PMCID: PMC4776001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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