Article
Complete and SOS-mediated response of Staphylococcus aureus to the antibiotic ciprofloxacin.
Journal of bacteriology - 1 Jan 2007
Cirz Ryan T, Jones Marcus B, Gingles Neill A, Minogue Timothy D, Jarrahi Behnam, Peterson Scott N, Romesberg Floyd E
Abstract excerpt
Staphylococcus aureus infections can be difficult to treat due to both multidrug resistance and the organism's remarkable ability to persist in the host. Persistence and the evolution of resistance may be related to several complex regulatory networks, such as the SOS response, which modifies transcription in response to environmental stress. To understand how S. aureus persists during antibiotic therapy and...
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