Article

Fluoroquinolone-Specific Resistance Trajectories in E. coli and their Dependence on the SOS-Response

2024-10-04

Abstract excerpt

<title>Abstract</title> <p>Background Fluoroquinolones are indispensable antibiotics used in treating bacterial infections in both human and veterinary medicine. However, resistance to these drugs presents a growing challenge. The SOS response, a DNA repair pathway activated by DNA damage, is known to influence resistance development, yet its role in fluoroquinolone resistance is not fully understood. This study...

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Literature Corpus work: 115d9237-165b-57cd-9c41-de84b6599c00
DOI: 10.21203/rs.3.rs-4939869/v1

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