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Genetic alterations in Thai adult patients with acute myeloid leukemia and myelodysplastic syndrome-excess blasts detected by next-generation sequencing technique.

Annals of hematology - 1 Aug 2021

Owattanapanich Weerapat, Herzig Julia, Jahn Nikolaus, Panina Ekaterina, Ruchutrakool Theera, Kungwankiattichai Smith, Issaragrisil Surapol, Döhner Hartmut, Döhner Konstanze

Abstract excerpt

Several molecular aberrations affect the prognosis of patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) with excess blasts (EB). This study aimed to determine the incidence and clinical impact of molecular genetic aberrations in Thai patients with AML and MDS-EB, detected by the next-generation sequencing (NGS) technique. This prospective, observational study was conducted between 2018...

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Share to DNA (Cytosine-5-)-Methyltransferases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33839881
DOI: 10.1007/s00277-021-04513-z
PMCID: PMC8285357

Genes

FLT3
TP53
ASXL1
DNMT3A
ETV6
SRSF2
WT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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