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Article

Acute Myeloid Leukemia and Next-Generation Sequencing Panels for Diagnosis: A Comprehensive Review.

Journal of pediatric hematology/oncology - 1 Apr 2024

Chaudhary Spandan, Chaudhary Pooja, Ahmad Firoz, Arora Neeraj

Abstract excerpt

Acute myeloid leukemia (AML) is a genetically heterogeneous clonal disorder characterized by the accumulation of acquired somatic genetic alterations in hematopoietic progenitor cells, which alter the normal mechanisms of self-renewal, proliferation, and differentiation. Due to significant technological advancements in sequencing technologies in the last 2 decades, classification and prognostic scoring of AML has...

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Identifiers

PMID: 38447075
DOI: 10.1097/MPH.0000000000002840
PMCID: PMC10956683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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