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Article

Genetically Proxied Inhibition of Coagulation Factors and Risk of Cardiovascular Disease: A Mendelian Randomization Study.

Journal of the American Heart Association - 20 Apr 2021

Yuan Shuai, Burgess Stephen, Laffan Mike, Mason Amy M, Dichgans Martin, Gill Dipender, Larsson Susanna C

Abstract excerpt

Background We conducted Mendelian randomization analyses investigating the linear associations of genetically proxied inhibition of different coagulation factors with risk of common cardiovascular diseases. Methods and Results Genetic instruments proxying coagulation factor inhibition were identified from genome-wide association studies for activated partial thromboplastin time and prothrombin time in BioBank...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33834859
DOI: 10.1161/JAHA.120.019644
PMCID: PMC8174173

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