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Article

Association of genetically proxied cholesteryl ester transfer protein inhibition with risk of intracranial aneurysms: a Mendelian randomization study.

Neurosurgical review - 28 Jul 2026

Gu Xialong, Wen Xuebin, Ma Lei, Wang Dongfeng, Li Zhenqiang, Chen Maosong, Ye Gengfan

Abstract excerpt

BACKGROUND: Lipid-lowering drugs have been implicated in aneurysm pathophysiology, but whether genetically proxied Cholesteryl Ester Transfer Protein (CETP) inhibition is associated with intracranial aneurysms (IA) and their clinical subtypes remains unclear. This study used drug-target Mendelian randomization to investigate the potential association between genetically proxied CETP inhibition and the risks of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42509441
DOI: 10.1007/s10143-026-04420-9

Genes

CETP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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