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Article

Genetically Predicted Cardiac Troponin I Concentrations and Risk of Stroke and Atrial Fibrillation.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Mar 2022

Liu Dandan, Deng Yue, Wang Jiao, Chen Yanan, Yu Jian, Tan Boyu, Wang Mengmeng

Abstract excerpt

OBJECTIVES: Observational studies have shown that elevated circulating cardiac troponin I (cTnI) concentrations were linked to higher risk of stroke and atrial fibrillation, but the causality remains unclear. Therefore, we used mendelian randomization to assess the potential causal effects of cTnI concentrations on the risk of stroke, its subtypes and atrial fibrillation. MATERIALS AND METHODS: The instrumental...

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Identifiers

PMID: 34954601
DOI: 10.1016/j.jstrokecerebrovasdis.2021.106267

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