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Article

Coagulation Factors and the Risk of Ischemic Heart Disease: A Mendelian Randomization Study.

Circulation. Genomic and precision medicine - 1 Jan 2018

Zhao Jie V, Schooling C Mary

Abstract excerpt

BACKGROUND: Coagulation plays a role in ischemic heart disease (IHD). However, which coagulation factors are targets of intervention is unclear. We assessed how genetically predicted vWF (von Willebrand factor), ETP (endogenous thrombin potential), FVIII (factor VIII), d-dimer, tPA (tissue-type plasminogen activator), and PAI (plasminogen activator inhibitor)-1 affected IHD. We similarly estimated effects on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29874180
DOI: 10.1161/CIRCGEN.117.001956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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